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Section: Application Domains

Amnesia

Patients sometimes develop post-traumatic disorders associated with the surgery they underwent because they either woke up during the surgery or because the amnesiant effect of the general anaesthesia was only partial, declarative memory being maintained in some unexplained cases. It is still unknown how memory can be maintained under general anaesthesia and it needs to be investigated to improve the recovery from anaesthesia and to avoid as much as possible post-traumatic disorders. To learn more about memory under anaesthesia, we will focus our theoretical studies on the oscillation regimes observed in the hippocampus, mainly in the theta and gamma ranges, respectively (0.5-4Hz) and (20-80Hz), which are correlated with memory formation and retrieval.